MARGARINE INTAKE AND RISK OF NONFATAL ACUTE MYOCARDIAL-INFARCTION IN ITALIAN WOMEN

Citation
A. Tavani et al., MARGARINE INTAKE AND RISK OF NONFATAL ACUTE MYOCARDIAL-INFARCTION IN ITALIAN WOMEN, European journal of clinical nutrition, 51(1), 1997, pp. 30-32
Citations number
25
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Nutrition & Dietetics
ISSN journal
0954-3007
Volume
51
Issue
1
Year of publication
1997
Pages
30 - 32
Database
ISI
SICI code
0954-3007(1997)51:1<30:MIARON>2.0.ZU;2-I
Abstract
Objectives: Since a relation between trans-fatty acids and cardiovascu lar diseases has been described, we examined the relationship between margarine intake and nonfatal acute myocardial infarction (AMI) in Ita lian women. Design: Hospital-based case-control study. Setting: Northe rn Italy between 1983 and 1992. Subjects: Cases were 429 women, aged 1 8-74 y, in hospital with diagnosis of AMI and 866 controls in hospital for acute, non-cardiovascular, non-neoplastic, non-digestive, non-hor mone-related conditions. Analysis: Odds ratios (OR), with their 95% co nfidence intervals (CI), were computed by unconditional multiple logis tic regression analysis, including terms for age, education, body mass index, smoking, alcohol and coffee drinking, menopausal status, hormo ne replacement therapy and history of diabetes, hypertension and hyper lipidemia. Results: Medium or high intake of margarine was associated with an increased risk of AMI (multivariate OR 1.5, 95% CI 1.0-2.2). A nalysis in separate strata of covariates indicated that the associatio n was independent of body mass index, history of hypertension and hype rlipidemia, and was greater in older women and in current smokers. Con clusions: If real, the association with margarine could explain about 6% of AMI in this population of Italian women.