PLACENTAL ISOFERRITIN PATTERNS DURING FIRST-TRIMESTER INTRAUTERINE GESTATION

Citation
R. Maymon et al., PLACENTAL ISOFERRITIN PATTERNS DURING FIRST-TRIMESTER INTRAUTERINE GESTATION, Gynecologic and obstetric investigation, 42(4), 1996, pp. 271-273
Citations number
8
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Obsetric & Gynecology
ISSN journal
0378-7346
Volume
42
Issue
4
Year of publication
1996
Pages
271 - 273
Database
ISI
SICI code
0378-7346(1996)42:4<271:PIPDFI>2.0.ZU;2-7
Abstract
In this study, serum placental ferritin (PLF) levels were measured amo ng 33 pregnant women with normal, singleton, ongoing first-trimester g estations and compared with 22 nonbleeding, missed and 14 incomplete a bortions. Diagnoses were based on clinical, sonographic, endocrinologi c and histopathologic criteria. At admission and before uterine evacua tion of the pregnancy products, venous blood was collected from the gr oups for PLF determination. The mean +/- SD serum PLF levels were 18 /- 14, 21 +/- 37, and 3.9 +/- 6.2 U/ml in normal gestations, missed an d incomplete abortions, respectively. Significant differences in PLF l evels were found among normal pregnancies and incomplete abortions (p < 0.05), whereas borderline significance was found in the missed abort ion group (p = 0.53). No correlation was found between serum beta hCG and PLF for the various pregnancy groups. Low PLF levels in pathologic gestation may reflect abnormal trophoblastic activity. Whether these play a causal role or are the casual outcome of pathologic gestation s hould be the subject of further evaluation.