ITRO-2-PHENYLSPIRO[CYCLOPROPANE-3,2'-QUINUCLIDINE] - SYNTHESIS AND REACTIONS WITH NUCLEOPHILES

Citation
Y. Besidsky et al., ITRO-2-PHENYLSPIRO[CYCLOPROPANE-3,2'-QUINUCLIDINE] - SYNTHESIS AND REACTIONS WITH NUCLEOPHILES, Journal of heterocyclic chemistry, 31(6), 1994, pp. 1321-1326
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
0022-152X
Volume
31
Issue
6
Year of publication
1994
Pages
1321 - 1326
Database
ISI
SICI code
0022-152X(1994)31:6<1321:I-SAR>2.0.ZU;2-X
Abstract
itro-2-phenylspiro[cyclopropane-3,2'-quinuclidine] was synthesized by a two-step procedure from 2-benzylidenequinuclidin-3-one. Ring-opening reactions of the cyclopropane ring using a variety of N-, O-, and C-n ucleophiles (amines, methoxide, nitromethanate, cyanide anions, and li thium diphenylcopper) were studied, and a general mechanism for the tr ansformations is proposed.