OSTEOCALCIN LEVELS IN CHRONIC OSTEOMYELITIS

Citation
Km. Peters et al., OSTEOCALCIN LEVELS IN CHRONIC OSTEOMYELITIS, Archives of orthopaedic and trauma surgery, 114(1), 1994, pp. 53-55
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Orthopedics,Surgery
ISSN journal
0936-8051
Volume
114
Issue
1
Year of publication
1994
Pages
53 - 55
Database
ISI
SICI code
0936-8051(1994)114:1<53:OLICO>2.0.ZU;2-O
Abstract
Osteocalcin is a vitamin K-dependent bone protein synthesized by osteo blasts. In generalized bone disorders serum osteocalcin correlates wit h osteoblast activity. Bone resorption and new bone formation occur in chronic osteomyelitis, dependent on the level of inflammatory activit y. In 17 patients with active chronic osteomyelitis undergoing surgery , the serum levels of osteocalcin, alkaline phosphatase and C-reactive protein were measured before and after treatment. The osteocalcin lev els were within the normal range preoperatively (10.8 +/- 11.0 mug/l), in the early postoperative period, and at discharge. It is therefore not a helpful marker in the clinical management of this condition.