DIMETHYL ETHER CHEMICAL-IONIZATION MASS-SPECTROMETRY

Authors
Citation
Ep. Burrows, DIMETHYL ETHER CHEMICAL-IONIZATION MASS-SPECTROMETRY, Mass spectrometry reviews, 14(2), 1995, pp. 107-115
Citations number
27
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Spectroscopy
Journal title
ISSN journal
0277-7037
Volume
14
Issue
2
Year of publication
1995
Pages
107 - 115
Database
ISI
SICI code
0277-7037(1995)14:2<107:DECM>2.0.ZU;2-E
Abstract
The uses of dimethyl ether (DME) as an unusual positive ion reagent fo r chemical ionization mass-spectrometry (CIMS) are reviewed. The fragm ent-molecule adducts formed by ion-molecule reactions of organic subst rates with the ionized gas are highly characteristic for the substrate s and frequently can be used to differentiate among isomers. The fragm entation mechanisms of the adducts have been studied by collision-indu ced dissociation and with deuterium labeling, and, in some cases, are well-understood. DME CIMS has been applied to a wide variety of classe s of organic compounds, including substituted aromatics, amino alcohol s, lactones, lactams, polyethylene glycols, benzodiazepines, azepines, trichothecenes, and certain alkaloids, nucleoside antibiotics, and po lynuclear aromatic hydrocarbons. (C) 1995 John Wiley & Sons, Inc.