N. Sato et al., KOJISTATIN-A, A NEW CYSTEINE PROTEASE INHIBITOR PRODUCED BY ASPERGILLUS-ORYZAE, Bioscience, biotechnology, and biochemistry, 60(10), 1996, pp. 1747-1748
A new cysteine protease inhibitor, named kojistatin A, was found in th
e extract of a solid culture of Aspergillus oryzae ATCC 20386. The str
ucture of kojistatin A was determined on the basis of chemical and spe
ctroscopic evidence. Kojistatin A specifically inhibited cysteine prot
eases such as papain, ficin, and bromelain.