THE RODENT GRANULAR CONVOLUTED TUBULE CELL - AN UPDATE

Citation
Ew. Gresik et al., THE RODENT GRANULAR CONVOLUTED TUBULE CELL - AN UPDATE, European journal of morphology, 34(3), 1996, pp. 221-224
Citations number
47
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Anatomy & Morphology
ISSN journal
0924-3860
Volume
34
Issue
3
Year of publication
1996
Pages
221 - 224
Database
ISI
SICI code
0924-3860(1996)34:3<221:TRGCTC>2.0.ZU;2-F
Abstract
The cells of the granular convoluted tubule (GCT) of the rodent subman dibular gland (SMG) are under complex developmental and multihormonal regulation. Recent findings indicate that GCT cells also synthesize tr ansforming growth factor alpha (TGF-alpha), hepatocyte growth factor, erythroid differentiation factor endothelin, and insulin-like growth f actor, as well as several novel androgen-dependent proteins of unknown function. The GCTs of hypophysectomized mice provide a convenient mod el to study multihormonal regulation of gene expression. The GCT syste m of the rodent SMG also is a fruitful model for study of hormone rece ptors.