DISSEMINATED EPIDEMIC KAPOSIS-SARCOMA TREATED WITH RADIATION AND CHEMOTHERAPY

Citation
Rg. Swanton et al., DISSEMINATED EPIDEMIC KAPOSIS-SARCOMA TREATED WITH RADIATION AND CHEMOTHERAPY, Southern medical journal, 89(7), 1996, pp. 718-722
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
0038-4348
Volume
89
Issue
7
Year of publication
1996
Pages
718 - 722
Database
ISI
SICI code
0038-4348(1996)89:7<718:DEKTWR>2.0.ZU;2-M
Abstract
When a 40-year-old patient with end-stage acquired immunodeficiency sy ndrome (AIDS) had bloating and abdominal pain, a large epidemic Kaposi 's sarcoma (EKS) lesion was found obstructing tile pylorus, Treatment consisted of single-agent chemotherapy for the disseminated lesions an d external beam irradiation to the obstructing lesion, Within days of radiation therapy, symptoms began to resolve, and by completion of the rapy, the patient was virtually asymptomatic. Although EKS is common i n homosexual men infected with the AIDS virus, these patients usually succumb to overwhelming opportunistic infections, Nevertheless, pallia tive courses of radiation, which call produce a complete response in 5 0% to 100% of treated KS lesions, can substantially improve the qualit y of life in these patients.