INTRAVASCULAR IMAGING OF SERIAL CHANGES OF DISEASE IN SAPHENOUS-VEIN GRAFTS AFTER CORONARY-ARTERY BYPASS-GRAFTING

Citation
N. Komiyama et al., INTRAVASCULAR IMAGING OF SERIAL CHANGES OF DISEASE IN SAPHENOUS-VEIN GRAFTS AFTER CORONARY-ARTERY BYPASS-GRAFTING, The American heart journal, 132(1), 1996, pp. 30-40
Citations number
24
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
ISSN journal
0002-8703
Volume
132
Issue
1
Year of publication
1996
Part
1
Pages
30 - 40
Database
ISI
SICI code
0002-8703(1996)132:1<30:IIOSCO>2.0.ZU;2-B
Abstract
To clarify the structural changes of saphenous vein grafts after coron ary artery bypass grafting, intravascular ultrasound and angioscopic i mages were obtained from 23 grafts in vivo and 5 grafts and 3 new vein s in vitro; the images were compared with histologic findings. Intrava scular ultrasound demonstrated a single-layered appearance at new vein s and all of the angiographically normal grafts within 6 months after surgery. A triple-layered appearance that might be related to the rema rkably proliferative and degenerated intima was revealed histologicall y at 73.3% of the normal sites of grafts between 5 and 10 years after operation. In 83.3% of the stenoses at several years after operation, angioscopy showed yellow atheromatous plaques, often with a friable su rface; a heterogeneous, lucent echo pattern was revealed on intravascu lar ultrasound. Thus intravascular ultrasound and angioscopy may he us ed to identify the morphologic changes of grafts at different points a fter implantation more precisely than conventional angiography.