B. Xie et al., SUCCESSFUL RADIOFREQUENCY ABLATION OF ACCESSORY PATHWAYS WITH THE FIRST ENERGY DELIVERY - THE ANATOMIC AND ELECTRICAL CHARACTERISTICS, European heart journal, 17(7), 1996, pp. 1072-1079
Successful ablation of accessory pathways has been achieved at the fir
st energy delivery site in some patients, but factors permitting succe
ss at the first site are unclear. Accessory pathway location, surface
and endocardial electrogram characteristics in each location were anal
ysed and compared between the patients with first site block (group A,
34 patients) and those in whom multiple sites (median seven sites) we
re required (group B, 133 patients). No patients with right free-wall
pathways had first site block. In group A surface electrocardiograms w
ere more pre-excited (QRS duration: 132+/-20 vs 120+/-17 ms, P<0 . 01)
. For left free-wall and septal pathways, the interval from the onset
of the earliest delta wave on surface electrocardiogram to local ventr
icular activation (QRS-V) was more negative and the local atrioventric
ular interval (AV) was shorter in group A; the positive predictive val
ue of a QRS-V less than or equal to 0 ms, an AV less than or equal to
30 ms and the presence of a possible accessory pathway potential was 6
7% for left free-wall and of a QRS-V less than or equal to-10 ms with
an AV less than or equal to 30 ms was 100% for septal pathways. During
retrograde mapping of concealed left free-wall and right anteroseptal
pathways (first site block was not achieved in other locations) the p
ositive predictive value of a local ventriculoatrial interval less tha
n or equal to 30 ms was 55%. Accessory pathway location correlated str
ongly with the chances of first site block, suggesting that anatomical
features are important. Maximizing pre-excitation may be of benefit i
n achieving first site block. Delivery of energy to a site with specia
l endocardial electrogram features was associated with an increased li
kelihood of first site block.