ESTIMATING THE INCIDENCE OF CELIAC-DISEASE WITH CAPTURE-RECAPTURE METHODS WITH 4 GEOGRAPHIC AREAS IN ITALY

Citation
G. Corrao et al., ESTIMATING THE INCIDENCE OF CELIAC-DISEASE WITH CAPTURE-RECAPTURE METHODS WITH 4 GEOGRAPHIC AREAS IN ITALY, Journal of epidemiology and community health, 50(3), 1996, pp. 299-305
Citations number
41
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Public, Environmental & Occupation Heath
ISSN journal
0143-005X
Volume
50
Issue
3
Year of publication
1996
Pages
299 - 305
Database
ISI
SICI code
0143-005X(1996)50:3<299:ETIOCW>2.0.ZU;2-Z
Abstract
Study objective - To estimate the incidence rate of newly diagnosed ca ses of coeliac disease in Italy. Design - This was a descriptive study of coeliac disease incidence in the period 1990-91. Setting - During 1990-91 newly diagnosed cases of coeliac disease were signalled by sev eral sources including diagnostic records of departments of paediatric s, general medicine and gastroenterology, national health service reco rds for the supply of gluten free diets and the archives of the Italia n Coeliac Society. Patients - Altogether 1475 cases were flagged throu ghout Italy, 478 of whom were Selected, corresponding to 270 individua l patients from a target population resident in four areas: Provices o f Turin and Cuneo (Piedmont Region, northern Italy); Province of Bresc ia (Lombardia Region, northern Italy); Umbria Region (central Italy) a nd Sardinia Region (insular Italy). Only for these areas were patients flagged from several sources and the reference population was identif iable. Main results - The overall crude incidence rates for all ages p er 100 000 residents per year were 2.4, 2.7, 1.5, and 1.7 in the four areas, respectively. The childhood cumulative incidence rates (aged le ss than or equal to 15 years) per 100 000 live births were 143, 141, 7 2, and 80 respectively. The mean ages at diagnosis were similar for bo th childhood and adult cases throughout the areas - these were around 4 and 34 years respectively. For each area, the incidence rate was con stantly higher in main city than elsewhere. Using the capture-recaptur e method, an estimated completeness of case archives of 0.84 was obtai ned, whereas this figure was only 0.47 for hospital sources. Conclusio ns - This population based study of the disease rather than different environmental patterns affecting the clinical presentation.