ACAMPROSATE AS AN AID IN THE TREATMENT OF ALCOHOLISM

Authors
Citation
J. Chick, ACAMPROSATE AS AN AID IN THE TREATMENT OF ALCOHOLISM, Alcohol and alcoholism, 30(6), 1995, pp. 785-787
Citations number
17
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Substance Abuse
Journal title
ISSN journal
0735-0414
Volume
30
Issue
6
Year of publication
1995
Pages
785 - 787
Database
ISI
SICI code
0735-0414(1995)30:6<785:AAAAIT>2.0.ZU;2-N
Abstract
Acamprosate is a gamma-aminobutyric acid (GABA) analogue for which evi dence is accumulating of a clinically useful benefit when used as an a djunct for conventional treatments to prevent relapse in alcohol depen dence. This paper reviews published randomized controlled studies invo lving 1304 patients. To date no abstinence syndrome associated with ac amprosate has been identified nor serious adverse effects. It is not e ffective in all patients, and the characteristics of the individuals m ost likely to respond and the treatment setting and modalities in whic h it is likely to be most helpful, have yet to be specified.