MULTICENTER CALIBRATION OF THE 3RD BCR REFERENCE MATERIAL FOR THROMBOPLASTIN, RABBIT, PLAIN, CODED CRM 149S - LONG-TERM STABILITY OF PREVIOUS BCR REFERENCE MATERIALS

Citation
Amhp. Vandenbesselaar, MULTICENTER CALIBRATION OF THE 3RD BCR REFERENCE MATERIAL FOR THROMBOPLASTIN, RABBIT, PLAIN, CODED CRM 149S - LONG-TERM STABILITY OF PREVIOUS BCR REFERENCE MATERIALS, Thrombosis and haemostasis, 74(6), 1995, pp. 1465-1467
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Hematology,"Cardiac & Cardiovascular System","Peripheal Vascular Diseas
Journal title
ISSN journal
0340-6245
Volume
74
Issue
6
Year of publication
1995
Pages
1465 - 1467
Database
ISI
SICI code
0340-6245(1995)74:6<1465:MCOT3B>2.0.ZU;2-Y
Abstract
In a collaborative study by eleven laboratories performed within the f ramework of the European Community Bureau of Reference (BCR), a third reference material for thromboplastin, rabbit, plain, has been calibra ted against RBT/90, the current WHO international reference preparatio n for thromboplastin, rabbit, plain. This third reference material (co ded CRM 149S) has a mean International Sensitivity Index (ISI) of 1,25 7 with a standard error of the mean of 0.013. The previous BCR referen ce material for thromboplastin, rabbit, plain (coded CRM 149R) and the reference material for thromboplastin, bovine, combined (coded OBT/79 ) were also included in the trial for assessment of the long-term stab ility of the ISI values. The relationship between ISI values determine d in the present study was nearly identical to that of the historical values, These results offer reassurance with regard to the long-term s tability of these reference materials.