MR ANATOMY OF THE SUBSTANTIA INNOMINATA AND FINDINGS IN ALZHEIMER-DISEASE - A PRELIMINARY-REPORT

Citation
M. Sasaki et al., MR ANATOMY OF THE SUBSTANTIA INNOMINATA AND FINDINGS IN ALZHEIMER-DISEASE - A PRELIMINARY-REPORT, American journal of neuroradiology, 16(10), 1995, pp. 2001-2007
Citations number
38
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurosciences,"Radiology,Nuclear Medicine & Medical Imaging
ISSN journal
0195-6108
Volume
16
Issue
10
Year of publication
1995
Pages
2001 - 2007
Database
ISI
SICI code
0195-6108(1995)16:10<2001:MAOTSI>2.0.ZU;2-S
Abstract
PURPOSE: To demonstrate normal MR anatomy of the substantia innominata and its changes in Alzheimer disease on MR imaging. METHODS: Using a 1.5-T superconductive MR unit, thickness of the substantia innominata was measured on coronal thin-section images obtained in 22 patients wi th Alzheimer disease and 14 age-matched control subjects. Comparison o f these images with postmortem specimens of human brain was also perfo rmed. RESULTS: On T2-weighted images through the anterior commissure, the substantia innominata was clearly identified between the globus pa llidus and the anterior perforated substance. In Alzheimer disease, th inning of the substantia innominata was more frequently observed than in the age-matched controls. CONCLUSION: Thin-section T2-weighted coro nal MR images can demonstrate shrinkage of the substantia innominata, a finding that may aid in the diagnosis of Alzheimer disease.