DETECTION OF HYPERVASCULAR HEPATOCELLULAR-CARCINOMA BY USING SPIRAL VOLUMETRIC CT - COMPARISON OF US AND MR-IMAGING

Citation
K. Ueda et al., DETECTION OF HYPERVASCULAR HEPATOCELLULAR-CARCINOMA BY USING SPIRAL VOLUMETRIC CT - COMPARISON OF US AND MR-IMAGING, Abdominal imaging, 20(6), 1995, pp. 547-553
Citations number
35
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Gastroenterology & Hepatology","Radiology,Nuclear Medicine & Medical Imaging
Journal title
ISSN journal
0942-8925
Volume
20
Issue
6
Year of publication
1995
Pages
547 - 553
Database
ISI
SICI code
0942-8925(1995)20:6<547:DOHHBU>2.0.ZU;2-C
Abstract
Background: Most hepatocellular carcinomas (HCCs) are hypervascular an d arise in the liver with chronicity, Spiral volumetric CT (SVCT) is a new rapid-scan technique that offers whole-liver scanning during the arterial-dominant phase, The main aim of the present study is to evalu ate the detectability of hypervascular HCC with SVCT as compared with ultrasonography (US) and magnetic resonance (MR) imaging. Methods: For ty-three hypervascular HCCs in 512 patients with chronic liver disease were examined with US, precontrast SVCT, postcontrast SVCT during the arterial-dominant phase (CT-ADP) and during the equivalent-phase (CT- EP) noncontrast MR imaging and angiography including SVCT during arter iography and arterial portography. Angiographic and follow-up findings were used as the gold standard if the lesion was not confirmed histol ogically. Results: The sensitivity was 61% with precontrast CT, 84% wi th CT-ADP, 58% with CT-EP, 70% with US, 72% with MR, and 95% with the combination of these five modalities, Five HCCs (12%) were detected wi th only CT-ADP, The vascularity of HCC was correctly evaluated as hype rvascular in 38 nodules (88%) with the combination of precontrast CT a nd CT-ADP. Conclusions: We suggest that the combination of precontrast SVCT and CT-ADP is an essential modality to screen for HCC in patient s with chronic liver disease. CT-EP did not contribute to the detectio n of hypervascular HCC.