K. Ueda et al., DETECTION OF HYPERVASCULAR HEPATOCELLULAR-CARCINOMA BY USING SPIRAL VOLUMETRIC CT - COMPARISON OF US AND MR-IMAGING, Abdominal imaging, 20(6), 1995, pp. 547-553
Citations number
35
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Gastroenterology & Hepatology","Radiology,Nuclear Medicine & Medical Imaging
Background: Most hepatocellular carcinomas (HCCs) are hypervascular an
d arise in the liver with chronicity, Spiral volumetric CT (SVCT) is a
new rapid-scan technique that offers whole-liver scanning during the
arterial-dominant phase, The main aim of the present study is to evalu
ate the detectability of hypervascular HCC with SVCT as compared with
ultrasonography (US) and magnetic resonance (MR) imaging. Methods: For
ty-three hypervascular HCCs in 512 patients with chronic liver disease
were examined with US, precontrast SVCT, postcontrast SVCT during the
arterial-dominant phase (CT-ADP) and during the equivalent-phase (CT-
EP) noncontrast MR imaging and angiography including SVCT during arter
iography and arterial portography. Angiographic and follow-up findings
were used as the gold standard if the lesion was not confirmed histol
ogically. Results: The sensitivity was 61% with precontrast CT, 84% wi
th CT-ADP, 58% with CT-EP, 70% with US, 72% with MR, and 95% with the
combination of these five modalities, Five HCCs (12%) were detected wi
th only CT-ADP, The vascularity of HCC was correctly evaluated as hype
rvascular in 38 nodules (88%) with the combination of precontrast CT a
nd CT-ADP. Conclusions: We suggest that the combination of precontrast
SVCT and CT-ADP is an essential modality to screen for HCC in patient
s with chronic liver disease. CT-EP did not contribute to the detectio
n of hypervascular HCC.