Intracerebral co-grafting of Schwann's cells and human fetal adrenal m
edullary tissue was performed in 10 patients with Parkinson's disease.
One to six months after grafting, symptoms were improved significantl
y for 1 to 3 grade. Among them, 2 patients resumed nearly normal daily
activities. Long-term follow-up showed that the symptoms were not imp
roved satisfactorily in some patients. It is considered that careful s
election of patients, administration of amantadine, and co-grafting of
Schwann's cells which prompts the survival of chromaffin cells are es
sential to better results.