115 children with burn injuries were admitted to the Children's Hospit
al of Chongqing Medical University. Of the 1554 samples, 276 strains o
f staphylococcus aureus were isolated from the burn wounds and other s
ites. The rate of burn wound infection caused by S. aureus was 25.2% (
29/115). Tle 54 epidemic strains of S. aureus all carried 1.6 and 1.9
Md plasmid DNAs belonging to phage type 618, and were resistant to at
least 10 antimicrobial agents, including oxacillin, cephalothin and ce
phaloridine, but sensitive to tobramycin and amikacin. Identical plasm
id profiles and phage types of isolated S. aureus indicated that a pat
ient carrying a multi-resistant strain of S. aureus in his anterior na
res caused an epidemic of S. aureus wound infection in 13 patients. S.
aureus isolated from burn wounds of 8 cases were derived from the con
taminated hands of their family members.