LEWIS-ACID PROMOTED CONJUGATE ADDITION OF VINYLMAGNESIUM BROMIDE TO CHIRAL ALPHA,BETA-UNSATURATED N-ACYL OXAZOLIDINONES

Authors
Citation
Yl. Han et Vj. Hruby, LEWIS-ACID PROMOTED CONJUGATE ADDITION OF VINYLMAGNESIUM BROMIDE TO CHIRAL ALPHA,BETA-UNSATURATED N-ACYL OXAZOLIDINONES, Tetrahedron letters, 38(42), 1997, pp. 7317-7320
Citations number
34
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
0040-4039
Volume
38
Issue
42
Year of publication
1997
Pages
7317 - 7320
Database
ISI
SICI code
0040-4039(1997)38:42<7317:LPCAOV>2.0.ZU;2-P
Abstract
Lewis acid promoted conjugated additions of vinylmagnesium bromide to chiral alpha,beta-unsaturated N-acyl oxazolidinones are described. A s eries of enatiomerically pure beta-branched 4-pentenoic acid derivativ es have been synthesized with high diastereoselectivity. (C) 1997 Else vier Science Ltd.