CELL-CELL COMMUNICATION IN GRAM-POSITIVE BACTERIA

Citation
Gm. Dunny et Bab. Leonard, CELL-CELL COMMUNICATION IN GRAM-POSITIVE BACTERIA, Annual review of microbiology, 51, 1997, pp. 527-564
Citations number
130
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Microbiology
ISSN journal
0066-4227
Volume
51
Year of publication
1997
Pages
527 - 564
Database
ISI
SICI code
0066-4227(1997)51:<527:CCIGB>2.0.ZU;2-6
Abstract
In gram-positive bacteria, many important processes are controlled by cell-to-cell communication, which is mediated by extracellular signal molecules produced by the bacteria. Most of these signaling molecules are peptides or modified peptides. Signal processing, in most cases, i nvolves either transduction across the cytoplasmic membrane or import of the signal and subsequent interaction with intracellular effecters. Concentrations of signal in the nanomolar range or below are frequent ly sufficient for biological activity. The microbial processes control led by extracellular signaling include the expression of virulence fac tors, the expression of gene transfer functions, and the production of antibiotics.