Results: 1-12 |
Results: 12
Design and synthesis of novel 2,3-dihydro-1H-isoindoles with high affinityand selectivity for the dopamine D-3 receptor
Authors: Austin, NE Avenell, KY Boyfield, I Branch, CL Hadley, MS Jeffrey, P Johnson, CN Macdonald, GJ Nash, DJ Riley, GJ Smith, AB Stemp, G Thewlis, KM Vong, AKK Wood, MD
Citation: Ne. Austin et al., Design and synthesis of novel 2,3-dihydro-1H-isoindoles with high affinityand selectivity for the dopamine D-3 receptor, BIOORG MED, 11(5), 2001, pp. 685-688
Pharmacokinetics of the novel, high-affinity and selective dopamine D3 receptor antagonist SB-277011 in rat, dog and monkey: in vitro/in vivo correlation and the role of aldehyde oxidase
Authors: Austin, NE Baldwin, SJ Cutler, L Deeks, N Kelly, PJ Nash, M Shardlow, CE Stemp, G Thewlis, K Ayrton, A Jeffrey, P
Citation: Ne. Austin et al., Pharmacokinetics of the novel, high-affinity and selective dopamine D3 receptor antagonist SB-277011 in rat, dog and monkey: in vitro/in vivo correlation and the role of aldehyde oxidase, XENOBIOTICA, 31(8-9), 2001, pp. 677-686
Hydrogen bonding control in the oxidative cyclisation of 1,5-dienes
Authors: Donohoe, TJ Winter, JJG Helliwell, M Stemp, G
Citation: Tj. Donohoe et al., Hydrogen bonding control in the oxidative cyclisation of 1,5-dienes, TETRAHEDR L, 42(6), 2001, pp. 971-974
Novel 2,3,4,5-tetrahydro-1H-3-benzazepines with high affinity and selectivity for the dopamine D-3 receptor
Authors: Austin, NE Avenell, KY Boyfield, I Branch, CL Hadley, MS Jeffrey, P Johnson, CN Macdonald, GJ Nash, DJ Riley, GJ Smith, AB Stemp, G Thewlis, KM Vong, AKK Wood, M
Citation: Ne. Austin et al., Novel 2,3,4,5-tetrahydro-1H-3-benzazepines with high affinity and selectivity for the dopamine D-3 receptor, BIOORG MED, 10(22), 2000, pp. 2553-2555
A syn selective dihydroxylation of cyclic allylic trichloroacetamides using catalytic osmium tetroxide
Authors: Blades, K Donohoe, TJ Winter, JJG Stemp, G
Citation: K. Blades et al., A syn selective dihydroxylation of cyclic allylic trichloroacetamides using catalytic osmium tetroxide, TETRAHEDR L, 41(24), 2000, pp. 4701-4704
Pharmacological actions of a novel, high-affinity, and selective human dopamine D-3 receptor antagonist, SB-277011-A
Authors: Reavill, C Taylor, SG Wood, MD Ashmeade, T Austin, NE Avenell, KY Boyfield, I Branch, CL Cilia, J Coldwell, MC Hadley, MS Hunter, AJ Jeffrey, P Jewitt, F Johnson, CN Jones, DNC Medhurst, AD Middlemiss, DN Nash, DJ Riley, GJ Routledge, C Stemp, G Thewlis, KM Trail, B Vong, AKK Hagan, JJ
Citation: C. Reavill et al., Pharmacological actions of a novel, high-affinity, and selective human dopamine D-3 receptor antagonist, SB-277011-A, J PHARM EXP, 294(3), 2000, pp. 1154-1165
Acute and chronic administration of the selective D-3 receptor antagonist SB-277011-A alters activity of midbrain dopamine neurons in rats: An in vivo electrophysiological study
Authors: Ashby, CR Minabe, Y Stemp, G Hagan, JJ Middlemiss, DN
Citation: Cr. Ashby et al., Acute and chronic administration of the selective D-3 receptor antagonist SB-277011-A alters activity of midbrain dopamine neurons in rats: An in vivo electrophysiological study, J PHARM EXP, 294(3), 2000, pp. 1166-1174
Design and synthesis of trans-N-[4-[2-(6-cyano-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A potent and selective dopamine D-3 receptor antagonist with high oral bioavailability and CNS penetration in the rat
Authors: Stemp, G Ashmeade, T Branch, CL Hadley, MS Hunter, AJ Johnson, CN Nash, DJ Thewlis, KM Vong, AKK Austin, NE Jeffrey, P Avenell, KY Boyfield, I Hagan, JJ Middlemiss, DN Reavill, C Riley, GJ Routledge, C Wood, M
Citation: G. Stemp et al., Design and synthesis of trans-N-[4-[2-(6-cyano-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A potent and selective dopamine D-3 receptor antagonist with high oral bioavailability and CNS penetration in the rat, J MED CHEM, 43(9), 2000, pp. 1878-1885
Novel 1,2,3,4-tetrahydroisoquinolines with high affinity and selectivity for the dopamine D-3 receptor
Authors: Austin, NE Avenell, KY Boyfield, I Branch, CL Coldwell, MC Hadley, MS Jeffrey, P Johns, A Johnson, CN Nash, DJ Riley, GJ Smith, SA Stacey, RC Stemp, G Thewlis, KM Vong, AKK
Citation: Ne. Austin et al., Novel 1,2,3,4-tetrahydroisoquinolines with high affinity and selectivity for the dopamine D-3 receptor, BIOORG MED, 9(2), 1999, pp. 179-184
Heterocyclic analogues of 2-aminotetralins with high affinity and selectivity for the dopamine D-3 receptor
Authors: Avenell, KY Boyfield, I Hadley, MS Johnson, CN Nash, DJ Riley, GJ Stemp, G
Citation: Ky. Avenell et al., Heterocyclic analogues of 2-aminotetralins with high affinity and selectivity for the dopamine D-3 receptor, BIOORG MED, 9(18), 1999, pp. 2715-2720
Directed dihydroxylation of allylic trichloroacetamides
Authors: Donohoe, TJ Blades, K Helliwell, M Moore, PR Winter, JJG Stemp, G
Citation: Tj. Donohoe et al., Directed dihydroxylation of allylic trichloroacetamides, J ORG CHEM, 64(9), 1999, pp. 2980-2981
Pharmacological characterization of extracellular acidification rate responses in human D-2(long), D-3 and D-4.4 receptors expressed in Chinese hamster ovary cells
Authors: Coldwell, MC Boyfield, I Brown, AM Stemp, G Middlemiss, DN
Citation: Mc. Coldwell et al., Pharmacological characterization of extracellular acidification rate responses in human D-2(long), D-3 and D-4.4 receptors expressed in Chinese hamster ovary cells, BR J PHARM, 127(5), 1999, pp. 1135-1144
Risultati: 1-12 |