Results: 1-25 |
Results: 25

Authors: Pahernik, SA Thasler, WE Doser, M Gomez-Lechon, MJ Castell, MJ Planck, H Koebe, HG
Citation: Sa. Pahernik et al., High density culturing of porcine hepatocytes immobilized on nonwoven polyurethane-based biomatrices, CELLS T ORG, 168(3), 2001, pp. 170-177

Authors: Jover, R Bort, R Gomez-Lechon, MJ Castell, JV
Citation: R. Jover et al., Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting, HEPATOLOGY, 33(3), 2001, pp. 668-675

Authors: Gomez-Lechon, MJ Ponsoda, X Bort, R Castell, JV
Citation: Mj. Gomez-lechon et al., The use of cultured hepatocytes to investigate the metabolism of drugs andmechanisms of drug hepatotoxicity, ATLA-ALT L, 29(3), 2001, pp. 225-231

Authors: Ponsoda, X Pareja, E Gomez-Lechon, MJ Fabra, R Carrasco, E Trullenque, R Castell, JV
Citation: X. Ponsoda et al., Drug biotransformation by human hepatocytes. In vitro/in vivo metabolism by cells from the same donor, J HEPATOL, 34(1), 2001, pp. 19-25

Authors: Vondracek, M Xi, Z Larsson, P Baker, V Mace, K Pfeifer, A Tjalve, H Donato, MT Gomez-Lechon, MJ Grafstrom, RC
Citation: M. Vondracek et al., Cytochrome P450 expression and related metabolism in human buccal mucosa, CARCINOGENE, 22(3), 2001, pp. 481-488

Authors: Andersson, TB Sjoberg, H Hoffmann, KJ Boobis, AR Watts, P Edwards, RJ Lake, BG Price, RJ Renwick, AB Gomez-Lechon, MJ Castell, JV Ingelman-Sundberg, M Hidestrand, M Goldfarb, PS Lewis, DFV Corcos, L Guillouzo, A Taavitsainen, P Pelkonen, O
Citation: Tb. Andersson et al., An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant, DRUG META D, 29(5), 2001, pp. 712-720

Authors: Pelkonen, O Myllynen, P Taavitsainen, P Boobis, AR Watts, P Lake, BG Price, RJ Renwick, AB Gomez-Lechon, MJ Castell, JV Ingelman-Sundberg, M Hidestrand, M Guillouzo, A Corcos, L Goldfarb, PS Lewis, DFV
Citation: O. Pelkonen et al., Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems, XENOBIOTICA, 31(6), 2001, pp. 321-343

Authors: Donato, MT Ponsoda, X O'Connor, E Castell, JV Gomez-Lechon, MJ
Citation: Mt. Donato et al., Role of endogenous nitric oxide in liver-specific functions and survival of cultured rat hepatocytes, XENOBIOTICA, 31(5), 2001, pp. 249-264

Authors: Gomez-Lechon, MJ Donato, T Jover, R Rodriguez, C Ponsoda, X Glaise, D Castell, JV Guguen-Guillouzo, C
Citation: Mj. Gomez-lechon et al., Expression and induction of a large set of drug-metabolizing enzymes by the highly differentiated human hepatoma cell line BC2, EUR J BIOCH, 268(5), 2001, pp. 1448-1459

Authors: Rodriguez-Antona, C Donato, MT Pareja, E Gomez-Lechon, MJ Castell, JV
Citation: C. Rodriguez-antona et al., Cytochrome P-450 mRNA expression in human liver and its relationship with enzyme activity, ARCH BIOCH, 393(2), 2001, pp. 308-315

Authors: Gomez-Lechon, MJ Castell, JV Donato, T Pahernik, S Thasler, W Koebe, HG Doser, M Dauner, M Planck, H
Citation: Mj. Gomez-lechon et al., New non-woven polyurethane-based biomaterials for the cultivation of hepatocytes: expression of differentiated functions, J MAT S-M M, 11(1), 2000, pp. 37-41

Authors: Clemedson, C Barile, FA Chesne, C Cottin, M Curren, R Ekwall, B Ferro, M Gomez-Lechon, MJ Imai, K Janus, J Kemp, RB Kerszman, G Kjellstrand, P Lavrijsen, K Logemann, P McFarlane-Abdulla, E Roguet, R Segner, H Thuvander, A Walum, E Ekwall, B
Citation: C. Clemedson et al., MEIC evaluation of acute systemic toxicity - Part VII. Prediction of humantoxicity by results from testing of the first 30 reference chemicals with 27 further in vitro assays, ATLA-ALT L, 28, 2000, pp. 161-200

Authors: Megias, L Guerri, C Fornas, E Azorin, I Bendala, E Sancho-Tello, M Duran, JM Tomas, M Gomez-Lechon, MJ Renau-Piqueras, J
Citation: L. Megias et al., Endocytosis and transcytosis in growing astrocytes in primary culture. Possible implications in neural development, INT J DEV B, 44(2), 2000, pp. 209-221

Authors: Galvez, J Garcia-Domenech, R Gomez-Lechon, MJ Castell, JV
Citation: J. Galvez et al., Use of molecular topology in the selection of new cytostatic drugs, J MOL ST-TH, 504, 2000, pp. 241-248

Authors: Donato, MT Viitala, P Rodriguez-Antona, C Lindfors, A Castell, JV Raunio, H Gomez-Lechon, MJ Pelkonen, O
Citation: Mt. Donato et al., CYP2A5/CYP2A6 expression in mouse and human hepatocytes treated with various in vivo inducers, DRUG META D, 28(11), 2000, pp. 1321-1326

Authors: Althaus, M Retzow, A Castell, JV Gomez-Lechon, MJ Amalou, Z Rose, T Appel, K
Citation: M. Althaus et al., In vitro identification of the cytochrome P450 isoform responsible for themetabolism of alpha-dihydroergocryptine, XENOBIOTICA, 30(11), 2000, pp. 1033-1045

Authors: Rodriguez-Antona, C Jover, R Gomez-Lechon, MJ Castell, JV
Citation: C. Rodriguez-antona et al., Quantitative RT-PCR measurement of human cytochrome P-450s: Application todrug induction studies, ARCH BIOCH, 376(1), 2000, pp. 109-116

Authors: Bort, R Castell, JV Pfeifer, A Gomez-Lechon, MJ Mace, K
Citation: R. Bort et al., High expression of human CYP2C in immortalized human liver epithelial cells, TOX VITRO, 13(4-5), 1999, pp. 633-638

Authors: Miranda, MA Sarabia, Z Hernandez, D Morera, IM Gomez-Lechon, MJ Castell, JV
Citation: Ma. Miranda et al., An in vitro approach to drug photoallergy: Use of drug-directed antibodiesto assess photobinding of nonsteroidal anti-inflammatories to skin cells, TOX VITRO, 13(4-5), 1999, pp. 701-705

Authors: Donato, MT Castell, JV Gomez-Lechon, MJ
Citation: Mt. Donato et al., Characterization of drug metabolizing activities in pig hepatocytes for use in bioartificial liver devices: comparison with other hepatic cellular models, J HEPATOL, 31(3), 1999, pp. 542-549

Authors: Gomez-Lechon, MJ
Citation: Mj. Gomez-lechon, Oncostatin M: Signal transduction and biological activity, LIFE SCI, 65(20), 1999, pp. 2019-2030

Authors: Bort, R Ponsoda, X Jover, R Gomez-Lechon, MJ Castell, JV
Citation: R. Bort et al., Diclofenac toxicity to hepatocytes: A role for drug metabolism in cell toxicity, J PHARM EXP, 288(1), 1999, pp. 65-72

Authors: Bort, R Mace, K Boobis, A Gomez-Lechon, MJ Pfeifer, A Castell, J
Citation: R. Bort et al., Hepatic metabolism of diclofenac: Role of human CYP in the minor oxidativepathways, BIOCH PHARM, 58(5), 1999, pp. 787-796

Authors: Ponsoda, X Bort, R Jover, R Gomez-Lechon, MJ Castell, JV
Citation: X. Ponsoda et al., Increased toxicity of cocaine on human hepatocytes induced by ethanol: Role of GSH, BIOCH PHARM, 58(10), 1999, pp. 1579-1585

Authors: Gomez-Lechon, MJ Jover, R Donato, T Ponsoda, X Rodriguez, C Stenzel, KG Klocke, R Paul, D Guillen, I Bort, R Castell, JV
Citation: Mj. Gomez-lechon et al., Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix, J CELL PHYS, 177(4), 1998, pp. 553-562
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